Strom Sports QUATREFOLIC^® Methylfolate

The body can’t just use folic acid as it is—it has to go through a conversion process into a form called Methyltetrahydrofolate, or MTHF, in order to use it. Quatrefolic^® doesn’t go through the same conversion process as folic acid, effectively bypassing that genetic variation.

- 120 Capsules / 120 Serves -

Folic acid vs. active folate: What’s the difference? 

While often used interchangeably, folic acid and folate are not the same.

Folic acid is the inactive precursor to active folate, but has historically been used in dietary supplements and fortified foods.  

However, to become biologically active, folic acid needs to go through several transformation steps in the body. These conversion steps change folic acid into active folate (known as 5-MTHF) as found in Quatrefolic®. 

For a long time, fortified foods and supplements were made with folic acid as the only source of vitamin B9 because it was shown that folic acid is more stable and bioavailable than the forms of folate found in foods.  

But new research in the last 10 years has shown that not everybody can convert folic acid to active folate in the same way – meaning that taking supplements containing folic acid can be ineffective for some people.  

These people have a specific genetic make-up which means they cannot produce enough of the enzyme that helps convert folic acid into active 5-MTHF folate. This is known as MTHFR polymorphism. 

Because the conversion into active folate is not required for reduced and methylated folates like Quatrefolic®, it is a more effective form to take folate than folic acid, which requires conversion. It is also very beneficial for people with MTHFR polymorphism, since they have a lower ability to transform folic acid into the active form of folate. 

Recommended Use

Take one tablet in the morning. 

For more information on Strom products check out the Stromucation website.